Giant Cell Tumour in a Patient with Paget’s Disease of the Skull Bone - A Rare Case Report

Giant Cell Tumour of Skull in Paget’s Disease: A Case Report

Authors

  • Kaisar Haroon Department of Neurosurgery, National Institute of Neurosciences and Hospital, Agargaon Dhaka, Bangladesh.
  • Md Shafiul Alam Gamma Knife, National Institute of Neurosciences and Hospital, Dhaka
  • Md Nowfel Islam Department of Neuropathology, National Institute of Neurosciences and Hospital, Dhaka

DOI:

https://doi.org/10.3329/bmrcb.v50i2.75574

Keywords:

Giant cell tumour, Paget’s disease, Titanium mesh, Alkaline phosphatase, Bangladesh

Abstract

Background: Paget’s disease of bone (PDB) is a localized disorder of bone remodeling resulting in abnormal bone architecture. It is a chronic and slowly progressive disorder. The disease was first described in England, in 1877, by Sir James Paget who defined it with the name of “osteitis deformans.

Objectives: this patient underwent craniotomy for excision of the swelling. The bony destruction was reconstructed using titanium mesh.

Methods: A forty seven year old lady suffering from Paget’s disease, presented to us with a progressive firm swelling in the front of the left frontal bone including the orbit. She was operated upon and her swelling was diagnosed as Giant cell tumour.

Results: After surgery she became well and orbital swelling had subsided and she had a good cosmetic appearance.  

Conclusion: surgery is the main options for GCT. Patients with Paget’s disease have a tendency to have GCT, and this should be kept in the mind during diagnosis.

Bangladesh Med Res Counc Bull 2024; 50: 111-115

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Published

2024-08-01

How to Cite

Haroon, K., Alam , M. S., & Islam, M. N. (2024). Giant Cell Tumour in a Patient with Paget’s Disease of the Skull Bone - A Rare Case Report: Giant Cell Tumour of Skull in Paget’s Disease: A Case Report. Bangladesh Medical Research Council Bulletin, 50(2), 111–115. https://doi.org/10.3329/bmrcb.v50i2.75574

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Section

Case Report