Role of Micronutrients on the Improvement of Sperm Count and Motility in Idiopathic Oligospermia, Asthenospermia and Oligoasthenospermia
Micronutrients and Male Infertility: Sperm Count & Motility
DOI:
https://doi.org/10.3329/bmrcb.v50i2.69711Keywords:
Idiopathic Oligospermia, Asthenospermia, Oligoasthenospermia, MicronutrientsAbstract
Background: The management approach to infertility has changed remarkably in this age of assisted reproductive techniques (ART) with the aim of bringing hope for previously untreatable cases.
Objective: To assess the effectiveness of micronutrients on sperm count and motility in treating patients with idiopathic oligospermia, asthenospermia and oligoasthenospermia.
Methods: This prospective observational study was carried out at Reproductive Endocrinology and Infertility OPD and IVF center of Dhaka Medical College Hospital (DMCH) for the period of two years from July 2017 to June 2019 over 100 patients. All infertile men aged between 25-45 years with idiopathic oligospermia, asthenospermia or oligoasthenospermia attending Reproductive Endocrinology and Infertility OPD and IVF center of DMCH during the study period were assigned for the study. After obtaining informed written consent selection of the patient was done by using inclusion and exclusion criteria with the help of attending physicians.Semen analysis was performed at day zero (during inclusion date) and after 1 month of initial report at the center. Those patients with confirmed abnormal semen parameters in terms of oligospermia, asthenospermia or oligoasthenospermia were treated with micronutrients (Capsule Sperm Care, 1 capsule twice daily after meal for 3 months) by the attending physicians at Reproductive Endocrinology and Infertility OPD and IVF center of department of obstetrics and gynaecology, DMCH as per treatment protocol. Semen analysis was again performed at the end of three months of micronutrient treatment in the same center. Then information was collected from semen analysis reports and attending physicians. Comparison of the result of these two semen analysis reports in terms of sperm count and motility was observed after three months of micronutrient treatment.
Results: Of total 100 patients, mean age was 34.40±5.40 SD (years). Among them, 63% were suffering from primary subfertility and 37% had secondary subfertility. Overall frequency of oligospermia, oligoasthenospermia and asthenospermia were 28%, 60% and 12%, respectively. Base line sperm count was 12.13±8.03 million/ml, mean progressive motility (PR) was 27.31±9.81% and mean total motility (PR+NP) was 38.76±12.27% . Significant improvement was noted in sperm count, progressive motility (PR) and total motility (PR+NP) of patients after three months of therapy (p<0.001).
Conclusion: Significant improvement was noticed in sperm count and motility after providing three months of micronutrient therapy.
Bangladesh Med Res Counc Bull 2024; 50: 67-73
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Copyright (c) 2024 Mahbuba Khan Eusuf Zai; Md. Habibullah, Sharmin Ali Tithy, Rashida Khanom
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