Circulating levels of homocysteine in preeclamptic women

Authors

  • Ali Khosrowbeygi Department of Biochemistry, School of Medicine, Lorestan University of Medical Sciences, Khorramabad
  • H Ahmadvand Department of Biochemistry, School of Medicine, Lorestan University of Medical Sciences, Khorramabad

DOI:

https://doi.org/10.3329/bmrcb.v37i3.6196

Keywords:

Serum, Homocysteine, Preeclampsia, Pregnancy, ELISA

Abstract

It has been hypothesized that maternal hyperhomocysteinemia to be associated with preeclampsia. the aims of the present study were to examine maternal serum levels of total homocysteine in preeclamptic women and its association with the severity of the disease. The study population consisted of 30 preeclamptic patients and 30 matched healthy pregnant women. Serum levels of total homocysteine were assessed using enzyme immunoassay method. Maternal serum levels of total homocysteine were significantly higher in preeclamptic group than in normal pregnant women. Women with severe preeclampsia had higher serum levels of total homocysteine than mild preeclamptic patients. Levels of total homocysteine correlated positively with systolic blood pressure values in preeclamptic women. In summary, maternal serum levels of total homocysteine were increased in preeclamptic women, and hyperhomocysteinemia was associated with severity of preeclampsia.

DOI: http://dx.doi.org/10.3329/bmrcb.v37i3.6196

BMRCB 2011; 37(3): 106-109

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Published

2011-12-05

How to Cite

Khosrowbeygi, A., & Ahmadvand, H. (2011). Circulating levels of homocysteine in preeclamptic women. Bangladesh Medical Research Council Bulletin, 37(3), 106–109. https://doi.org/10.3329/bmrcb.v37i3.6196

Issue

Section

Research Papers