TY - JOUR AU - Chowdhury, Sabikun Nahar AU - Islam, Md Nazrul AU - Roshed, Md Mahabubur AU - Hossain, Md Mokter AU - Salahuddin, Gazi PY - 2021/07/18 Y2 - 2024/03/28 TI - Laboratory parameters of COVID-19 patients in Khulna, Bangladesh JF - Bangladesh Medical Journal Khulna JA - Bangladesh med. j. Khulna VL - 53 IS - 1-2 SE - Original Articles DO - 10.3329/bmjk.v53i1-2.54883 UR - https://www.banglajol.info/index.php/BMJK/article/view/54883 SP - 13-16 AB - <p><strong>Background: </strong>Recent studies have demonstrated the role of several laboratory tests in addition to RT-PCR in the diagnosis of COVID 19. Some of these, laboratory tests are indicators of the current state of the disease, while others have proved to be useful prognostic markers.</p><p><strong>Objective: </strong>The objective of our study was to evaluate the hematological, biochemical and radiological changes in COVID-19 patients.</p><p><strong>Methods: </strong>It was an observational and analytical study done retrospectively. The whole number of patients were included on the basis of inclusion and exclusion creteria. All were confirmed cases of COVID-19 patients either admitted in different hospitals or were in home isolation.</p><p><strong>Results: </strong>Total study cases was 112. Complete blood count revealed, leukocytosis was present in 9 (8.0%) cases and leucopenia in 8 (7.14%) cases. Neutrophilia was present in 27 (24.1%) cases; neutropenia in 9(8.0%) cases, lymphocylosis in 17 (15.2%) cases; lymphopenia in 28 (25%) cases. Neutrophil Lymphocyte ratio (NLR) revealed mean value of NLR 2.3(±1.1) with a range of 0.6-4.0. Decreased total circulating eosinophil count (&lt;40/cmm) was found in 6 (5.3%) cases. Thrombocytopenia was found in 31 (27.7%) cases, Elevated ESR was found in 53 (47.3%) cases; CRP value was increased in 47 (42.0%) cases. Increased serum ferritin was found in 29 (25.9%) cases. D-dimer was increased in 35 (31.3%) cases; Xray chest showed bilateral pneumonia in 26 (23.2%) cases. High resolution computed tomography (HRCT) of chest revealed ground glass opacities in 11(9.8%) cases.</p><p><strong>Conclusion: </strong>Multiple changes in laboratory findings were observed such as altered NLR, elevated acute phase reactants, increased seromarkers (S ferritin, D-dimers) and also opacities in chest imaging.</p><p>Bang Med J Khulna 2020: 53 : 13-16</p> ER -