<i>In vitro</i> free radical scavenging activity of methanol extract of the leaves of <i>Mimusops elengi</i> Linn.

Authors

  • MR Saha Department of Pharmacy, Stamford University Bangladesh, Dhaka
  • SMR Hasan Department of Pharmacy, Stamford University Bangladesh, Dhaka
  • R Akter Department of Pharmacy, Stamford University Bangladesh, Dhaka
  • MM Hossain Department of Pharmacy, Stamford University Bangladesh, Dhaka
  • MS Alam Department of Agricultural Chemistry, Bangladesh Agricultural University, Mymensingh
  • MA Alam Department of Pharmacy, Stamford University Bangladesh, Dhaka
  • MEH Mazumder Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjvm.v6i2.2336

Keywords:

Mimusops elengi, antioxidant, reducing power, total antioxidant capacity, reactive oxygen species

Abstract

In the present study, antioxidant potential of the methanol extract of the leaves of Mimusops elengi Linn. was evaluated by using 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay, reducing power and total antioxidant capacity. The extract showed significant activities in all antioxidant assays compared to the reference antioxidant ascorbic acid in a dose dependent manner. In DPPH scavenging assay the IC50 value of the extract was found to be 43.26μg/ml while the IC50 value of the reference standard ascorbic acid was 58.92 μg/ml. Total antioxidant activity was also found to increase in a dose dependent manner. Moreover, M. elengi extract showed strong reducing power. These results suggest that Mimusops elengi may act as a chemopreventative agent, providing antioxidant properties and offering effective protection from free radicals.

Key words: Mimusops elengi, antioxidant, reducing power, total antioxidant capacity, reactive oxygen species  

doi: 10.3329/bjvm.v6i2.2336

Bangl. J. Vet. Med. (2008). 6 (2): 197-202

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Laboratory Animal Medicine