Investigation on Baby Chick Ranikhet Disease Vaccine administration in chicks of vaccinated and nonvaccinated origin

Abstract

Persistence of maternally derived antibody to Baby Chick Ranikhet Disease Vaccine and its influence on vaccination programme in chicks of vaccinated and nonvaccinated origin were determined during the period from July 2005 to May 2006. The study suggested an effective vaccination schedule of Baby Chick Ranikhet Disease Vaccine in chicks of vaccinated and nonvaccinated origin. The optimum age for vaccination of chicks of vaccinated and nonvaccinated origin were determined by inoculating vaccine following two different vaccination schedules. In one schedule chicks of group C of vaccinated origin and group F of nonvaccinated origin were vaccinated primarily at day 4 and was boosted at day 19 and in another schedule the chicks of group D of vaccinated origin were vaccinated once at day 14 without giving booster dose. It was found that maternally derived antibody passed over from the parents to progeny chicks and remain protective for the chicks of group A of vaccinated origin until 18 days of age and the chicks of group B of nonvaccinated origin until 5 days of age. This maternally derived antibody was retained particularly up to 24 days and 11 days in chicks of group A and B obtained from parent vaccinated and nonvaccinated flock respectively. Chicks of group C primarily vaccinated with Baby Chick Ranikhet Disease Vaccine revealed slightly positive effect to rise of antibody during their gradual increase of age due to the presence of high level of antibody at the time of primary vaccination where as in chicks of group F antibody level was increasing impetuously due to the low level of antibody at the time of vaccination. Chicks of group D vaccinated at the state of subsidence of maternally derived antibody with Baby Chick Ranikhet Disease Vaccine showed impetuous production of antibody titers. Chicks possessing high level of maternally derived antibody may be vaccinated singly against Newcastle disease when they are 14 to 18 days old and chicks possessing low level of maternally derived antibody may be vaccinated twice at 4 and 19 days of age.

Key words: BCRDV, F-strain NDV, chicks of vaccinated and nonvaccinated origin, MDA, haemagglutination inhibition test

DOI = 10.3329/bjvm.v4i2.1290

Bangl. J. Vet. Med. (2006). 4 (2): 93-96