Bangladesh Journal of Pharmacology <p>Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, single blinded peer-reviewed journal of the&nbsp;<a href="">Bangladesh Pharmacological Society</a>&nbsp;(BDPS). We publish Research article, Mini-review, Meta-analysis, Clinical Trial, Visual Experiment and Letter to the Editor.&nbsp;</p> <p>The author&nbsp;will not be charged in the form of submission fee, article processing fee or publication fee. It is completely free.</p> <p><strong>Journal Metrics</strong><br>Journal metrics allow you to compare journals, regardless of their subject classification.</p> <p>Impact Factor&nbsp;(2014): 1.052 (Web of Science)</p> <p><a href="">CiteScore Tracker 2017</a>: Updated on April 7, 2018</p> <p><img src="/public/site/images/misbah/CiteScore2017_Bangladesh_Journal_o.png" alt=""></p> <p><a href="">ResearchGate Journal Impact</a>&nbsp;(2014): 1.84</p> <p><strong>Abstracted/Indexed in</strong><br>Academic Search Complete, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts,&nbsp;<a href="">Directory of Open Access Journals</a>, EMBASE/Excerpta Medica, Global Health, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate,&nbsp;Science Citation Index Expanded, SCOPUS and Social Sciences Citation Index</p> <p><strong>Members</strong><br>Bangladesh Journal of Pharmacology is the member of&nbsp;<a href="">OASPA</a>&nbsp;(Open Access Scholarly Publishers Association),&nbsp;<a href="">COPE</a>&nbsp;(Committee on Publication Ethics), The International Society of Managing and Technical Editors (<a href="">ISMTE</a>) and Asian Council of Science Editors.</p> Bangladesh Pharmacological Society en-US Bangladesh Journal of Pharmacology 1991-0088 Authors who publish with this journal agree to the following terms:<br /><ol><li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a href="" target="_new"><span style="color: #337755;">Creative Commons Attribution License</span></a> that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li><li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li><li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See <a href="" target="_new"><span style="color: #337755;">The Effect of Open Access</span></a>).</li></ol> Amelioration of dry eye syndrome by oral administration of cultivated wild ginseng extract <p>The present study investigates the effect of ludartin on spinal cord injury in rat model. Ludartin treatment decreased the expression of myeloperoxidase and malondialdehyde in spinal cord tissues. The expression of glutathione and superoxide dismutase was enhanced. It also exhibited inhibitory effect on reduction of NeuN-positive cells. The proportion of TUNEL positive cells was also regulated. In addition, ludartin treatment prevented the onset of apoptosis which was evident by decrease in caspase-3 and Bax level and increase of Bcl‑2 level. Up-regulation of tumor necrosis factor‑α, inter-leukin‑1β and I interleukin‑6 by spinal cord injury was suppressed by ludartin treatment. There was improvement in locomotion of rats by treatment with ludartin. Ludartin treatment of spinal cord injury rats improves locomotion by inhibiting inflammatory cytokine expression and preventing cell apoptosis. Thus, ludartin has therapeutic importance in spinal cord injury treatment.</p> <p><strong>Video Clip of Methodology:</strong></p> <p>Western Blot Analysis: 6 min 17 sec:&nbsp;&nbsp;<a href="">Full Screen</a>&nbsp; &nbsp; &nbsp; <a href="">Alternate</a></p> Jae Sung Pyo Hyung Hoi Kim Kang Min Kim Jae Seon Kang ##submission.copyrightStatement## 2019-04-07 2019-04-07 14 2 61 66 10.3329/bjp.v14i2.39034 In vivo anti-diabetic effect of aqueous and methanolic macerated extracts of Atractylis gummifera <p class="Abstract">The anti-diabetic effect of <em>Atractylis gummifera</em> (plant used in traditional Moroccan medicine) has been evaluated in type 2 diabetic mice model. The mice were divided into five groups: Normal control, diabetic control, diabetic treated with aqueous macerate (500 mg/kg), diabetic treated with methanol macerate (500 mg/kg) and diabetic treated with metformin (300 mg/kg). The treatment of the mice was performed by daily gastric gavage for 5 weeks. The monitoring of the mice was carried out weekly by fasting glucose and measurement of biochemical parameters at the end of treatment. The aqueous macerate of <em>A. gummifera</em> was most effective that reduced the fasting blood glucose with 62.7%. In addition, this extract restored the biochemical parameters of diabetic mice to normal.</p> <p class="Abstract"><strong>Video Clip of Methodolpogy</strong>:</p> <p class="Abstract">5 min 53 sec:&nbsp; &nbsp;<a href="">Full Screen</a>&nbsp; &nbsp;<a href="">Alternate</a></p> Khadija Bouabid Fatima Lamchouri Hamid Toufik Mohamed Boulfia Souad Senhaji My El Abbes Faouzi ##submission.copyrightStatement## 2019-04-14 2019-04-14 14 2 67 73 10.3329/bjp.v14i2.38870