Bangladesh Journal of Pharmacology 2020-07-04T22:27:39+00:00 Prof. Mir Misbahuddin Open Journal Systems <p>Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, single blinded peer-reviewed journal of the&nbsp;Bangladesh Pharmacological Society&nbsp;(BDPS). We publish Research article, Mini-review, Meta-analysis, Clinical Trial, Visual Experiment and Letter to the Editor.&nbsp;<br> The author&nbsp;will not be charged in the form of submission fee, article processing fee or publication fee. It is completely free. We do not publish any advertisement.</p> <p><strong>Journal Metrics</strong><br> Journal metrics allow you to compare journals, regardless of their subject classification.<br>Impact Factor<sup>®</sup>&nbsp;as reported in the 2019 Journal Citation Reports<sup>®</sup>&nbsp;(Clarivate Analytics, 2020): <strong>1.306</strong></p> <p><img src="/public/site/images/misbah/IF1.png"></p> <p>CiteScore (2019):&nbsp;<strong>2.0</strong>&nbsp;&nbsp;<a href="">Current month's CiteScore Tracker</a><br> H index (2018): <strong>21</strong></p> <p>We have more than 10,000 readers from South Korea to Nigeria.</p> <p>We are preparing our journal's <a href="">backup website</a> for security purpose.&nbsp;</p> <p><strong>Abstracted/Indexed in</strong><br>Academic Search Complete, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts,&nbsp;<a href="">Directory of Open Access Journals</a>, EMBASE/Excerpta Medica, Global Health, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate,&nbsp;Science Citation Index Expanded, SCOPUS and Social Sciences Citation Index</p> <p><strong>Members</strong><br>Bangladesh Journal of Pharmacology is the member of&nbsp;<a href="">OASPA</a>&nbsp;(Open Access Scholarly Publishers Association),&nbsp;<a href="">COPE</a>&nbsp;(Committee on Publication Ethics), The International Society of Managing and Technical Editors (<a href="">ISMTE</a>) and Asian Council of Science Editors.</p> <h1 style="color: red;">Our activities are slow due to COVID-19 Lockdown</h1> Effect of capecitabine on breast cancer patients with different estrogen receptor status 2020-07-04T22:26:26+00:00 Gang Xu Xin Lv Ke Lu Ming Hai Shen Qing Hua Zhang Wan Neng Pan <p>This meta-analysis is to compare the efficacy of capecitabine versus non-capecitabine chemotherapy on breast cancer patients with different estrogen receptor (ER) status. We searched relevant literatures from EMBASE, PubMed and OVID library to analyze pathologic complete response rate (PCR), overall survival (OS), disease-free survival (DFS), progression-free survival (PFS), and time to disease progression (TTP). Eleven different studies were enrolled, which revealed that ER positive breast cancer patients who received treatment regimen containing capecitabine can effectively improve PFS, PCR, TTP. However, the difference between capecitabine-containing and non-capecitabine group has no significant for DFS, OS. ER negative breast cancer patients who received treatment regimen containing capecitabine can obviously improve DFS and TTP. However, there was no significant effect for PFS, PCR and OS. The results indicated that capecitabine in combination with other chemotherapy drugs for breast cancer is effective, which can delay the progression time in patients to some extent.</p> 2020-07-04T22:26:17+00:00 ##submission.copyrightStatement## Berberine hydrochloride inhibits inflammatory response via regulating the miRNA-140-5p/TLR4/NF-κB signaling pathway in oral lichen planus 2020-07-04T22:27:39+00:00 Qiong Zhang Liangjun Zhong Xing Chen Jintao Wang <p>The present study investigates the anti-inflammatory mechanism of berberine hydrochloride in the oral lichen planus. The local inflammatory environment of the oral lichen planus was mimicked, through which lipopolysaccharides stimulated keratinocyte HaCaT cells. Berberine hydrochloride suppressed the activation of the TLR4/NF-κB inflammatory signaling pathway by up-regulating miRNA-140-5p, which is an independent risk factor for the oral lichen planus. Furthermore, miRNA-140-5p inhibited the TLR4/NF-κB inflammatory signaling pathway by directly suppressing TLR4 expression. Therefore, the present study suggests that berberine hydrochloride inhibits the inflammatory response by up-regulating miRNA-140-5p to suppress the activation of the TLR4/NF-κB inflammatory signaling pathway in the oral lichen planus.</p> <p><strong>Video Clip of Methodology</strong></p> <p>RNA mixed with template: 2 min 17 sec:&nbsp; <a href="">Click to Watch</a></p> <p>Scrubbing and fixing glue device: 3 min 13 sec: <a href=";">Click to Watch</a></p> 2020-07-04T22:27:38+00:00 ##submission.copyrightStatement## Antibacterial activity of Dracaena colorama 2020-07-04T22:23:45+00:00 Ranjitha Dhevi V. Sundar Sathiavelu Arunachalam 2020-07-04T22:23:42+00:00 ##submission.copyrightStatement## Antimicrobial metabolites from Streptomyces sp. strain PDH23 derived from marine sponge Rhabdastrella globostellata 2020-07-04T22:25:14+00:00 Vu Thi Thu Huyen Le Thi Hong Minh Vu Thi Quyen Nguyen Mai Anh Nguyen Thi Kim Cuc Nguyen Thi Luyen Nguyen Tien Dat 2020-07-04T22:25:09+00:00 ##submission.copyrightStatement##