Bangladesh Journal of Pharmacology 2019-04-18T13:33:55+00:00 Prof. Mir Misbahuddin Open Journal Systems <p>Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is an open access, video component, single blinded peer-reviewed journal of the&nbsp;<a href="">Bangladesh Pharmacological Society</a>&nbsp;(BDPS). We publish Research article, Mini-review, Meta-analysis, Clinical Trial, Visual Experiment and Letter to the Editor.&nbsp;</p> <p>The author&nbsp;will not be charged in the form of submission fee, article processing fee or publication fee. It is completely free.</p> <p><strong>Journal Metrics</strong><br>Journal metrics allow you to compare journals, regardless of their subject classification.</p> <p>Impact Factor&nbsp;(2014): 1.052 (Web of Science)</p> <p><a href="">CiteScore Tracker 2017</a>: Updated on April 7, 2018</p> <p><img src="/public/site/images/misbah/CiteScore2017_Bangladesh_Journal_o.png" alt=""></p> <p><a href="">ResearchGate Journal Impact</a>&nbsp;(2014): 1.84</p> <p><strong>Abstracted/Indexed in</strong><br>Academic Search Complete, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts,&nbsp;<a href="">Directory of Open Access Journals</a>, EMBASE/Excerpta Medica, Global Health, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate,&nbsp;Science Citation Index Expanded, SCOPUS and Social Sciences Citation Index</p> <p><strong>Members</strong><br>Bangladesh Journal of Pharmacology is the member of&nbsp;<a href="">OASPA</a>&nbsp;(Open Access Scholarly Publishers Association),&nbsp;<a href="">COPE</a>&nbsp;(Committee on Publication Ethics), The International Society of Managing and Technical Editors (<a href="">ISMTE</a>) and Asian Council of Science Editors.</p> Amelioration of dry eye syndrome by oral administration of cultivated wild ginseng extract 2019-04-18T13:33:55+00:00 Jae Sung Pyo Hyung Hoi Kim Kang Min Kim Jae Seon Kang <p>The present study investigates the effect of ludartin on spinal cord injury in rat model. Ludartin treatment decreased the expression of myeloperoxidase and malondialdehyde in spinal cord tissues. The expression of glutathione and superoxide dismutase was enhanced. It also exhibited inhibitory effect on reduction of NeuN-positive cells. The proportion of TUNEL positive cells was also regulated. In addition, ludartin treatment prevented the onset of apoptosis which was evident by decrease in caspase-3 and Bax level and increase of Bcl‑2 level. Up-regulation of tumor necrosis factor‑α, inter-leukin‑1β and I interleukin‑6 by spinal cord injury was suppressed by ludartin treatment. There was improvement in locomotion of rats by treatment with ludartin. Ludartin treatment of spinal cord injury rats improves locomotion by inhibiting inflammatory cytokine expression and preventing cell apoptosis. Thus, ludartin has therapeutic importance in spinal cord injury treatment.</p> <p><strong>Video Clip of Methodology:</strong></p> <p>Western Blot Analysis: 6 min 17 sec:&nbsp;&nbsp;<a href="">Full Screen</a>&nbsp; &nbsp; &nbsp; <a href="">Alternate</a></p> 2019-04-07T00:00:00+00:00 ##submission.copyrightStatement## In vivo anti-diabetic effect of aqueous and methanolic macerated extracts of Atractylis gummifera 2019-04-18T13:33:52+00:00 Khadija Bouabid Fatima Lamchouri Hamid Toufik Mohamed Boulfia Souad Senhaji My El Abbes Faouzi <p class="Abstract">The anti-diabetic effect of <em>Atractylis gummifera</em> (plant used in traditional Moroccan medicine) has been evaluated in type 2 diabetic mice model. The mice were divided into five groups: Normal control, diabetic control, diabetic treated with aqueous macerate (500 mg/kg), diabetic treated with methanol macerate (500 mg/kg) and diabetic treated with metformin (300 mg/kg). The treatment of the mice was performed by daily gastric gavage for 5 weeks. The monitoring of the mice was carried out weekly by fasting glucose and measurement of biochemical parameters at the end of treatment. The aqueous macerate of <em>A. gummifera</em> was most effective that reduced the fasting blood glucose with 62.7%. In addition, this extract restored the biochemical parameters of diabetic mice to normal.</p> <p class="Abstract"><strong>Video Clip of Methodolpogy</strong>:</p> <p class="Abstract">5 min 53 sec:&nbsp; &nbsp;<a href="">Full Screen</a>&nbsp; &nbsp;<a href="">Alternate</a></p> 2019-04-14T01:10:48+00:00 ##submission.copyrightStatement##