TY - JOUR AU - Akacha, Maroua AU - Lahbib, Karima AU - Daami-Remadi, Mejda AU - Boughanmi, NĂ©ziha Ghanem PY - 2016/07/05 Y2 - 2024/03/28 TI - Antibacterial, antifungal and anti-inflammatory activities of Melia azedarach ethanolic leaf extract JF - Bangladesh Journal of Pharmacology JA - Bangladesh J Pharmacol VL - 11 IS - 3 SE - Research Articles DO - 10.3329/bjp.v11i3.27000 UR - https://www.banglajol.info/index.php/BJP/article/view/27000 SP - 666-674 AB - <p class="Abstract">The aim of the present study is to examine the antibacterial, antifungal and anti-inflammatory activities of the ethanolic leaf extract of <em>Melia azedarach</em>. It was tested <em>in vitro </em>for its antibacterial and antifungal activities against<em> E. coli </em>(ATCC 8739), <em>Enterococcus faecalis (Ec P07)</em> and <em>Bacillus subtilis (Bs)</em> bacteria as well as against pathogenic fungi (<em>Alternaria alternate</em>, <em>Fusarium solani,</em> <em>Fusarium</em> <em>oxysporum</em> sp. <em>melonis, F. oxysporum</em> f. sp. <em>lycopersici</em>, <em>F. sambucinum </em>and <em>Botrytis cinerea</em>) with different techniques similtaneously with anti-inflammatory activity with carageaneen method. All tested concentrations of <em>M. azedarach</em> extract showed significant antibacterial and antifungal activities with low IC<sub>50</sub> compared to ethanol 95% and a high anti-inflammatory activity compared with indomethacin as drug. Our investigation pointed that <em>M. azedarach</em> could be considered as a good medicinal agent.</p><p class="Abstract"><strong>Video Clip of Methodology:</strong></p><p class="Abstract">Anti-inflammatory effect: 3 min 03 sec &nbsp; <a href="https://youtube.com/watch?v=Pc51tGbuxQY">Click to watch</a>&nbsp;</p> ER -