TY - JOUR AU - Chander, M. Punnam AU - Pillai, C. R. AU - Vijayachari, P. PY - 2015/12/21 Y2 - 2024/03/28 TI - Antimalarial efficacy of nine medicinal plants traditionally used by the Karens of Andaman and Nicobar Islands, India JF - Bangladesh Journal of Pharmacology JA - Bangladesh J Pharmacol VL - 11 IS - 1 SE - Research Articles DO - 10.3329/bjp.v11i1.24055 UR - https://www.banglajol.info/index.php/BJP/article/view/24055 SP - 126-129 AB - <p class="Abstract">The aim of this study was to assess the antimalarial activity of nine medicinal plants used by Karens of Andaman and Nicobar Islands, against <em>Plasmodium falciparum</em> chloroquine-sensitive MRC-2 isolate. The methanol extracts were obtained by cold percolation method and<em> in vitro</em> antimalarial activity was assessed using M-III method. The results indicated that out of nine plant species tested, four plants, viz., <em>Z. spectabilis, S. wallichiana, C. pulcherrima</em> and <em>Amomum</em> sp. demonstrated significant antimalarial activity (50% inhibitory concentration values were 5.5 ± 0.7, 12.0 ± 2.5, 14.6 ± 1.3 and 37.3 ± 2.5 ?g/mL respectively) with no toxicity effect on erythrocytes.</p> ER -