@article{Paul_Hakim_2015, title={In vivo hypoglycemic study of Manilkara zapota leave and seed extracts}, volume={10}, url={https://www.banglajol.info/index.php/BJP/article/view/21475}, DOI={10.3329/bjp.v10i1.21475}, abstractNote={<p>The hypoglycemic activity of pet-ether extracts of leaves and methanol extracts of seeds of <em>Manilkara zapota</em> was evaluated in the study. The oral glucose tolerance test was performed in mice treated with 2 mg/kg glucose solution and the blood glucose level was determined after 15, 30, 60, 90 and 120 min of administration. Alloxan (70 mg/kg) was injected intravenously to induce diabetes in mice. The hypoglycemic study was carried out 7 days. In glucose tolerance test all extracts achieved significant p values (p<0.0001) at 60, 90 and 120 minutes compared to the glucose control. In hypoglycemic study all extracts started to reduce the blood glucose level rapidly even starting from the 2<sup>nd</sup> day of treatment and significant p values (p<0.0001) were achieved. So, the study evinced the hypoglycemic potency of the leave and seed extracts of <em>M. zapota.</em></p>}, number={1}, journal={Bangladesh Journal of Pharmacology}, author={Paul, Saikat Ranjan and Hakim, Md. Lukman}, year={2015}, month={Mar.}, pages={246–250} }