Advancing the Management of Anaplastic Thyroid Carcinoma: A Case Study of Multimodal Therapy and the Role of Emerging Nuclear Medicine Infrastructure in Bangladesh

Authors

  • Priyanka Podder Senior Medical Officer, Institute of Nuclear Medical Physics (INMP), AERE, Savar
  • Fatema Tuz Zohra Senior Medical Officer, Institute of Nuclear Medical Physics (INMP), AERE, Savar
  • Samiul Alim Experimental Officer, Institute of Nuclear Medical Physics (INMP), AERE, Savar
  • Abul Hasnat Senior Scientific Officer, Institute of Nuclear Medical Physics (INMP), AERE, Savar
  • Rayhan Alam Senior Scientific Officer, Institute of Nuclear Medical Physics (INMP), AERE, Savar
  • Sanchoy Chandra Biswasarma Scientific Officer, National Institute of Nuclear Medicine and Allied Sciences (NINMAS), BSMMU
  • M A Mannan Associate Professor, Labaid Cancer Hospital, Dhaka
  • M Monjur Ahsan Chief Scientific Officer, Atomic Energy Center (AEC), Dhaka

DOI:

https://doi.org/10.3329/bjnm.v28i1.79555

Keywords:

Anaplastic thyroid carcinoma, Lymph nodes, Chemotherapy, 3D-CRT, PET-CT.

Abstract

Anaplastic thyroid carcinoma (ATC) is an aggressive and rare form of thyroid cancer, representing 1-2% of thyroid malignancies but accounting for the majority of thyroid cancer-related deaths due to its rapid progression, invasiveness, and resistance to standard therapies. This report highlights the case of a 60-year-old male histopathologically diagnosed with ATC stage IV as there were lymph node metastases. The patient was managed with a multidisciplinary team approach and had total thyroidectomy followed by systemic chemotherapy and three-dimensional conformal radiotherapy. The reported case highlights the importance of aggressive, integrated therapeutic approaches in managing ATC, emphasizing personalized, multidisciplinary care, advanced radiotherapy techniques, and molecular-targeted therapies for improved outcomes.

Bangladesh J. Nuclear Med. 28(1): 164-169, 2025

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Published

2025-04-13

How to Cite

Podder, P., Zohra, F. T., Alim, S., Hasnat, A., Alam, R., Biswasarma, S. C., … Ahsan, M. M. (2025). Advancing the Management of Anaplastic Thyroid Carcinoma: A Case Study of Multimodal Therapy and the Role of Emerging Nuclear Medicine Infrastructure in Bangladesh. Bangladesh Journal of Nuclear Medicine, 28(1), 164–169. https://doi.org/10.3329/bjnm.v28i1.79555

Issue

Section

Case Reports