A Rare Case of Autoimmune Polyglandular Syndrome (APS) Type 3

Authors

  • Fariha Zerin Medical Officer, INMAS, Kushtia, Kushtia Medical College & Hospital Campus, Kushtia
  • Md Sunny Anam Chowdhury Institute of Nuclear Medicine & Allied Sciences (INMAS), Kushtia
  • Md Nazmul Hossain Institute of Nuclear Medicine & Allied Sciences (INMAS), Kushtia
  • Sujon Mahmud Institute of Nuclear Medicine & Allied Sciences (INMAS), Kushtia
  • Yeasmin Akter Institute of Nuclear Medicine & Allied Sciences (INMAS), Kushtia
  • Bahalul Hasan Institute of Nuclear Medicine & Allied Sciences (INMAS), Kushtia
  • Tanvir Ahmad Medical Officer, National Heart Foundation Hospital & Research Institute, Dhaka

DOI:

https://doi.org/10.3329/bjnm.v28i1.79554

Keywords:

Autoimmune thyroiditis, Vitiligo, APS Type 3, Scintigraphy

Abstract

Background: Autoimmune Polyglandular Syndrome Type 3 is a rare condition where patients are diagnosed with more than one autoimmune disease having similarity in pathogenesis. Antibody detection with various imaging modalities, including nuclear medicine techniques, is crucial to confirm the diseases. Case Report: A 61-year-old elderly postmenopausal woman presented with vitiligo, features of hypothyroidism and systemic lupus erythematosus (SLE). After proper clinical evaluation, the anti-TPO antibody report came out positive, and a cold nodule was found in thyroid scintigraphy, thus confirming the diagnosis of autoimmune thyroiditis. Conclusion: Autoimmune thyroiditis associated with vitiligo is more common in female individuals under APS Type 3, so screening is recommended for clinically manifested pathology.

Bangladesh J. Nuclear Med. 28(1): 159-163, 2025

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Published

2025-04-13

How to Cite

Zerin, F., Chowdhury, M. S. A., Hossain, M. N., Mahmud, S., Akter, Y., Hasan, B., & Ahmad, T. (2025). A Rare Case of Autoimmune Polyglandular Syndrome (APS) Type 3. Bangladesh Journal of Nuclear Medicine, 28(1), 159–163. https://doi.org/10.3329/bjnm.v28i1.79554

Issue

Section

Case Reports