Hyponatremia in Acute Subarachnoid Hemorrhage: Frequency and Pathophysiology

Subash Kanti Dey; Lipy Bakshi; Md. Noor Nabi Sayem; Md. Abdullah Al Muzahid; Shahida Bul Bul; Sukumar Mazumder; Md. Shahidullah

doi:10.3329/bjn.v38i2.87273

Hyponatremia in Acute Subarachnoid Hemorrhage: Frequency and Pathophysiology

Authors

Subash Kanti Dey Department of Neurology, BSMMU, Dhaka, Bangladesh
Lipy Bakshi Department of Obstetrics and Gynaecology, Dhaka National Medical College, Dhaka, Bangladesh
Md. Noor Nabi Sayem Department of Epidemiology & Research, National Heart Foundation Hospital and Research Institute, Dhaka, Bangladesh
Md. Abdullah Al Muzahid Department of Neurology, BSMMU, Dhaka, Bangladesh
Shahida Bul Bul Department of Neurology, BSMMU, Dhaka, Bangladesh
Sukumar Mazumder Department of Neurology, Rangpur Medical College, Bangladesh
Md. Shahidullah Department of Neurology, BSMMU, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjn.v38i2.87273

Keywords:

Aneurysmal subarachnoid hemorrhage, hyponatremia, SIADH

Abstract

Background: Hyponatremia is the most common electrolyte abnormality seen in patients with aneurysmal SAH. Clinically significant hyponatremia (Serum Sodium <135 mEq/L) requires treatment and there is a paucity of outcome studies based on this.

Materials and Methods: This prospective study was undertaken in the Department of Neurology, BSMMU. Patients with aneurysmal subarachnoid hemorrhage (SAH) were selected for this study from 1stJanuary 2020 to 31st October, 2022.

Results: A total of 64 patients were included in the study. Hyponatremia was observed in 24 (37.5%) patients. Among them, 14 (58.7%) developed hyponatremia within the first week after SAH. Serum osmolality was low in 70.8% of patients who developed
hyponatremia. Urinary osmolality was also high for the same number (70.8%). Low serum osmolality and high urine osmolality were significantly (p<0.05) higher than that of normal values of serum and urine osmolality in hyponatremia patients.

Conclusion: Hyponatremia is common after subarachnoid hemorrhage. SIADH is the commonest cause of hyponatremia after subarachnoid hemorrhage.

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2026-01-30

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Dey, S. K., Lipy Bakshi, Md. Noor Nabi Sayem, Md. Abdullah Al Muzahid, Shahida Bul Bul, Sukumar Mazumder, & Md. Shahidullah. (2026). Hyponatremia in Acute Subarachnoid Hemorrhage: Frequency and Pathophysiology. Bangladesh Journal of Neuroscience, 38(2), 90–94. https://doi.org/10.3329/bjn.v38i2.87273

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Vol. 38 No. 2 (2022)

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Hyponatremia in Acute Subarachnoid Hemorrhage: Frequency and Pathophysiology

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