Moving from oral poliovirus vaccine to inactivated poliovirus vaccine: The rationale and challenges

  • Kazi Zulfiquer Mamun Vice Principal, Professor and Head of the Department of Microbiology, Popular Medical College, Dhaka
  • Nabeela Mahboob Assistant Professor, Department of Microbiology, Popular Medical College, Dhaka
  • Kazi Taib Mamun Research Investigator, icddrb, Dhaka
  • Hasina Iqbal Associate Professor, Department of Microbiology, Popular Medical College, Dhaka
Keywords: Poliomyelitis, Vaccine-associated paralytic polio, Circulating vaccine-derived poliovirus

Abstract

Oral polio vaccine (OPV) has served as the cornerstone of polio eradication efforts over the past 30 years, trivalent inactivated polio vaccine (IPV) has re-ascended to prominence in the past year, now acting as the sole source of protective immunity against type 2 poliovirus in routine immunization programmes. The Polio Eradication and Endgame Strategic plan 2013–2018, developed by the Global Polio Eradication Initiative (GPEI) outlines the phased removal of OPVs, starting with type 2 poliovirus–containing vaccines and introduction of inactivated polio vaccine in routine immunization to mitigate against risk of vaccine-associated paralytic polio and circulating vaccine-derived poliovirus.

Bangladesh J Medicine Jan 2020; 31(1) : 22-28

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Abstract
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PDF
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Published
2019-12-30
How to Cite
Mamun, K., Mahboob, N., Mamun, K., & Iqbal, H. (2019). Moving from oral poliovirus vaccine to inactivated poliovirus vaccine: The rationale and challenges. Bangladesh Journal of Medicine, 31(1), 22-28. https://doi.org/10.3329/bjm.v31i1.44749
Section
Review Articles