Bangladesh Journal of Infectious Diseases <p>Published by the Bangladesh Infection Research Association. Full text articles will be available.</p> <p>This journal invites authors and reviewers to register with the journal. The online submission process is available for new submissions.</p> <p><strong>Indexed/Abstract in: </strong>ROAD (; Open DOAR, Directory of Open Access Scholars Repository; ResearchBib; BASE (Bielefeld Academic Search Engine); Academic Resource Index;;; Infobase Index; Eurasian Scientific Journal Index; International Committee for Medical Journal Editors (ICJME); Easy Bib; Google Scholar; AsiaJol; Open Science Directory; EBSCO Information Service; EBSCO Open Access Journals; Hasselt University Library; Islamic Science Index (ISI); World Association of Medical Editors (WAME); Journal Factor; International Institute of Organized Research (I2OR); Impact Factor Services for International Journals (IFSIJ); Open Access Library; Scientific Indexing Services (SIS)</p> <p>&nbsp;</p> en-US <p class="default"><strong>Copyright</strong></p><p>Copyright on any research article in the Bangladesh Journal of Infectious Diseases is retained by the author(s).</p><p>The authors grant the Bangladesh Infection Research Association a license to publish the article and identify itself as the original publisher.</p><p>Articles in the Bangladesh Journal of Infectious Diseases are Open Access articles published under the Creative Commons CC BY-NC License (<a href=""></a>)</p><p>This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.</p> (Dr M Abdullah Yusuf) (Md Fahmid Uddin Khondoker) Mon, 19 Aug 2019 08:25:47 +0000 OJS 60 Alarming Turn of Dengue Fever in Dhaka City in 2019 <p>Abstract Not Available</p> <p><em>Bangladesh Journal of Infectious Diseases, June 2019;6(1):</em><em>1-2</em></p> Arifa Akram ##submission.copyrightStatement## Sat, 17 Aug 2019 07:28:07 +0000 Multiple Drug Resistance Pattern in Urinary Tract Infection Patients in Saudi Arabia <p><strong>Background:</strong> Urinary tract infection (UTI) is the most common problem in hospitalized and outdoor patients. It is mainly found in females because of the shortness of the urethra and closeness to anus, which facilitate entrance of fecal micro–flora to urinary tract. Knowledge of local antimicrobial resistance patterns is essential for evidence- based empirical antibiotic prescribing.</p> <p><strong>Objective:</strong> The main aim of this study was to analyze the drug resistance pattern of bacterial isolates from suspected urinary tract infection (UTI) patients in Al-Kharj, Saudi Arabia.</p> <p><strong>Methodology:</strong> This cross- sectional study was carried out in Al-Kharj region of Saudi Arabia from 1st. September, 2016 to 28th. February, 2017. Midstream urine specimens were collected from patients at a general hospital. The specimens were cultured and the isolates were identified using standard microbiological techniques. The antibiotic susceptibilities of the isolates were also determined.</p> <p><strong>Results:</strong> The number of patients with urinary tract infection who yielded positive cultures from their mid stream urine specimens was 249(12.0%) out of 2064 specimens. The commonest isolates were Escherichia coli (53.4%) and Klebsiella pneumoniae (28.5%). Other bacterial pathogens were Proteus mirabilis (5.2%), Pseudomonas aeruginosa (4.4%), Streptococcus agalactiae (6.0%) and Enterococcus faecalis. (2.5%).</p> <p><strong>Conclusions:</strong> E. coli is the most common causative agent of urinary tract infection followed by Klebsiella pneumoniae. Ampicillin, Augmentin, Cotrimoxazole, Norfloxacin and Nalidixic acid have the highest resistance rates against both these pathogens. No isolate is found to be resistant to imipenem.</p> <p>Bangladesh Journal of Infectious Diseases 2019;6(1):3-7</p> Shamweel Ahmad ##submission.copyrightStatement## Sun, 18 Aug 2019 17:40:34 +0000 Findings of Brain Imaging among Tuberculous Meningitis Patients: A Study of 30 Cases in Bangladesh <p><strong>Background:</strong> Tuberculous meningitis is a serious health hazard and difficult to diagnose.</p> <p><strong>Objectives:</strong> The purpose of the present study was to observe the role of CT/MRI in TBM diagnosis.</p> <p><strong>Methodology:</strong> This was a retrospective study done from January 2010 to December 2011 for a period of two (02) years. Patients of TBM were reviewed in a medical college hospital of Bangladesh.</p> <p><strong>Results:</strong> A total number of reviewed 30 TBM patients; among them 11 cases were confirmed TBM patients and 19 were probable patients. Brain imaging (CT/MRI) was performed in 15 cases. The use of brain imaging allowed the Brain lesions in 93.3% patients.</p> <p><strong>Conclusion:</strong> Brain imaging was done in 15 out of 30 TBM patients and most of them (14/15) had got various forms of radiological abnormalities that aid in diagnosis and monitor of disease progression in TBM.</p> <p>Bangladesh Journal of Infectious Diseases, June 2019; 6(1):8-11</p> Abul Kalam Mohammed Shoab, Mostafa Hosen, Syed Abul Foez, Md Shaheen Wadud, Habibur Rahman, Shahjada Mohammad Dastegir Khan, Masud Rana, Biplob Kumar Roy ##submission.copyrightStatement## Sun, 18 Aug 2019 18:06:42 +0000 Comparison of KAtex, Bone Marrow Aspiration and DAT for the Diagnosis of Visceral Leishmaniasis <p><strong>Background:</strong> Newly developed KAtex test can be used as a non invasive tool for diagnosis of Kala-azar.</p> <p><strong>Objectives:</strong> The aim of the present study was to compare KAtex, Bone marrow aspiration and DAT to diagnose VL.</p> <p><strong>Methodology:</strong> This cross-sectional study was carried out in the Department of Microbiology at Dhaka Medical College, Dhaka, Bangladesh in collaboration with the Department of Parasitology, Institute of Epidemiology, Disease Control and Research (IEDCR), Dhaka, Bangladesh for a period of one year. Clinically suspected Kala-azar (VL) cases of different age and sex attending IEDCR, Dhaka from different Kala-azar endemic areas of Bangladesh were selected for this study. Patients having fever for more than 2 weeks, with or without splenomegaly, having history of loss of body weight following onset of fever were clinically suspected as Kala-azar cases. Microscopy and culture was performed in bone marrow (BM). KAtex was performed with urine sample. Agglutination of sensitized latex indicated presence of Leishmania donovani antigen in urine and thereby visceral leishmaniasis. No agglutination indicates absence of antigen in urine. DAT was done with serums of all cases.</p> <p><strong>Result:</strong> Among 130 clinically suspected VL cases, 70 (53.85%) cases were BM positive and 60(46.15%) cases were BM negative. All the 70 BM positive cases were positive by KAtex and DAT. Among 60 BM negative cases, 15 were positive by KAtex and 23 were positive by DAT. The sensitivity of KAtex was 100.0% and specificity was 75.0%. The sensitivity of DAT was 100.0% and specificity is 61.6%.</p> <p><strong>Conclusion:</strong> In conclusion, KAtex test is a good diagnostic tool for the detection of VL in comparison with DAT.</p> <p>Bangladesh Journal of Infectious Diseases, June 2019;6(1):12-15</p> Ishrat Sharmin, AKM Quamruzzaman, Rezina Parveen, M Abdulah Yusuf, Rashida Akter Khanam ##submission.copyrightStatement## Sun, 18 Aug 2019 18:18:21 +0000 Distribution and Determinant of Post-Operative Wound Infection among Patients underwent Routine Abdominal Surgery <p><strong>Background:</strong> Post-operative wound infection may occur after routine abdominal surgery.</p> <p><strong>Objective:</strong> The purpose of the present study was to see the distribution and determinants of post-operative wound infection among the patients underwent routine abdominal surgery.</p> <p><strong>Methodology:</strong> This non-randomized clinical trial was conducted in the different surgical units of the Department of Surgery at Sir Sallimullah Medical College &amp; Mitford Hospital, Dhaka, Bangladesh during January 2001 to December 2002 for a period of two (02) years. In the operation theatre, after anaesthesia skin was cleaned with Povidone iodine USP 5% w/w or Spirit (70% methylated spirit in water) or Chlorhexidine. During post-operative period dressing were left undisturbed unless it was felt necessary. Unusual pain in and around the wound was considered to be an indication of infection. A swab was taken from any discharge and was sent for bacteriological examination.</p> <p><strong>Result:</strong> In this study, 50 patients were admitted as routine cases and undergone routine abdominal operations in general operation theatre. Out of 50 patients undergone routine abdominal surgery, 5 developed wound infection post operatively. Overall infection rate was 10.0%. In routine abdominal operations, infection was 9.09% in upper midline or extended midline incision, 33.33% in lower midline, 6.25% right subcostal/Kocher's. In routine abdominal operations, the rate of infection in clean contaminated wound was 11.11%, contaminated wound was 33.33%. Wound infection rate was 20.0% cases in patients with malnutrition, 14.28% cases in obesity and 16.66% cases in diabetes mellitus.</p> <p><strong>Conclusion:</strong> In conclusion post-operative wound infection is common in routine surgical operation.</p> <p>Bangladesh Journal of Infectious Diseases, June 2019;6(1):16-21<br><br></p> Md Mafiur Rahman, SM Shafiul Azam Chaudhury, Md Atiqul Islam, Mohammad Khurshidul Alam, ABM Mir Mubinul Islam, Abu Sayeed Mohammad, Mohammad Ahtashamul Haque ##submission.copyrightStatement## Sun, 18 Aug 2019 18:32:12 +0000 Clinical Efficacy of Amoxicillin versus Cefodoxime Proxetil for the Treatment of Pneumonia <p><strong>Background</strong>: Pneumonia is one of the leading cause of death of under 5 children in Bangladesh. WHO recommended Amoxicillin and Co-trimoxazole as first line drugs for the treatment of pneumonia. But emergence of antimicrobial resistance against the common pathogens prompted WHO panel to find out evidence based recommendations for treating pneumonia.</p> <p><strong>Objectives</strong>: The purpose of the present study was to compare the effect of oral Amoxicillin and Cefpodoxime proxetil in children with pneumonia.</p> <p><strong>Methodology</strong>: This prospective randomized study was conducted in outpatient department of Pediatrics at Mymensingh Medical College Hospital, Mymensingh, Bangladesh from March 2010 to March 2012 for a period of two (02) years. Baseline data were collected from 197 patients, thereafter 85 patients from Amoxicillin group and 89 patients from Cefpodoxime proxetil group completed the trial.</p> <p><strong>Results</strong>: Among the enrolled (197) children, majority (53%) were boys. The baseline clinical characteristics before therapy were not significantly different in both the Amoxicillin and Cefpodoxime proxetil groups. Changes in duration of cough, duration of dyspnea, duration of fast breathing, mean heart rate, temperature and respiratory rate were observed. After treatment with&nbsp; Amoxicillin and Cefpodoxime proxetil similar significant improvement in mean body temperature, respiratory rate and wheeze were observed which were almost similar in both the groups (p &lt;0.001). While comparing the efficacy, treatment outcome did not differ significantly in both the groups (p &gt;0.127). Chi-square test revealed no statistically significant difference between patients treated with Amoxicillin and those treated with Cefpodoxime proxetil (p =0.171).</p> <p><strong>Conclusion:</strong> Response to therapy in both Amoxicillin and Cefpodoxime Proxetil groups was nearly similar and the difference was statistically insignificant.</p> <p><em>Bangladesh Journal of Infectious Diseases, June 2019;6(1):22-25</em></p> Sajani Islam, Bithi Debnath, Md Azizul Hoque ##submission.copyrightStatement## Sun, 18 Aug 2019 18:49:05 +0000 Asymptomatic Bacteriuria in School-going Children in Lalitpur, Nepal <p>Abstract not available</p> <p><em>Bangladesh Journal of Infectious Diseases, June 2019;6(1):22-25</em></p> Bhuvan Saud, Pravakar Sunuwar, Govinda Paudel, Gunaraj Dhungana, Vikram Shrestha ##submission.copyrightStatement## Sun, 18 Aug 2019 18:58:44 +0000