Bangladesh Journal of Infectious Diseases <p>Published by the Bangladesh Infection Research Association. Full text articles will be available.</p> <p>This journal invites authors and reviewers to register with the journal. The online submission process is available for new submissions.</p> <p><strong>Indexed/Abstract in: </strong>ROAD (; Open DOAR, Directory of Open Access Scholars Repository; ResearchBib; BASE (Bielefeld Academic Search Engine); Academic Resource Index;;; Infobase Index; Eurasian Scientific Journal Index; International Committee for Medical Journal Editors (ICJME); Easy Bib; Google Scholar; AsiaJol; Open Science Directory; EBSCO Information Service; EBSCO Open Access Journals; Hasselt University Library; Islamic Science Index (ISI); World Association of Medical Editors (WAME); Journal Factor; International Institute of Organized Research (I2OR); Impact Factor Services for International Journals (IFSIJ); Open Access Library; Scientific Indexing Services (SIS)</p> <p>&nbsp;</p> en-US <p class="default"><strong>Copyright</strong></p><p>Copyright on any research article in the Bangladesh Journal of Infectious Diseases is retained by the author(s).</p><p>The authors grant the Bangladesh Infection Research Association a license to publish the article and identify itself as the original publisher.</p><p>Articles in the Bangladesh Journal of Infectious Diseases are Open Access articles published under the Creative Commons CC BY-NC License (<a href=""></a>)</p><p>This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.</p> (Dr M Abdullah Yusuf) (Md Fahmid Uddin Khondoker) Fri, 21 Aug 2020 05:47:44 +0000 OJS 60 Role of National Reference Laboratory: Bangladesh Perspective <p>Abstract not available</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):1-2</p> Abul Khair M Shamsuzzaman ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Incidence and Pattern of Clinical Dengue Cases among Travelers and NonTravelers in a District of Bangladesh <p><strong>Background: </strong>Expansion of Dengue fever caused by a mosquito borne arbovirus to new countries and, from urban to rural settings constitutes an important health problem in the world including Bangladesh.</p> <p><strong>Objective: </strong>This study was conducted to evaluate spread of clinical Dengue to previously non-endemic Barisal district and get an idea of how recent this spread is by comparing proportions of non-travelers and travelers to an endemic area among the admitted patients.</p> <p><strong>Methodology: </strong>The incidence of dengue infection in Barisal division with and without travel history to known endemic area was investigated in the current cross sectional study from a conveniently selected sample of patients admitted to the medicine department of Sher-e-Bangla medical College Hospital form Barisal district from July 15, through August, to September 15, 2019. Clinical and laboratory data were collected by attending doctors and checked by investigators. The primary diagnostic tool was NS1 antigen detected by SD Bioline Dengue NS1 Ag Test Kit. Data entry and analysis was done by SPSS version 24.0 software.</p> <p><strong>Result: </strong>A total number of sample size was 212 admitted patents of whom 138(65.1%) were male, 74 (34.9 %) were female,116 (54.7%) of patients traveled to a known endemic zone, 96 (45.3%) did not; 206 (97.2%) were NS1 positive, 4 (1.9%) were IgM positive, 2 (0.9%) were IgM positive and IgG positive; Of travelling 116 patients, 92(79.3%) were male, 24(20.7%) were female, of travelling 96 patients 46(47.9%) were male, 50(52.1%) were female. p-value was &lt;0.001.</p> <p><strong>Conclusion: </strong>The study concluded that Dengue is becoming endemic in previously non-endemic zones like greater Barisal, though travelers still holds the major share of disease burden. Male preponderance in traveling to endemic zone was statistically significant.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):3-7</p> Syed Abdul Kader, Sonia Afrin Rob ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Clinico-Pathological Profiles and Outcomes of Acute Viral Encephalitis in Children <p><strong>Background: </strong>Encephalitis is an acute inflammatory process that affects brain tissue and is almost always accompanied by inflammation of the adjacent meninges. The disease is most commonly caused by viral infection.</p> <p><strong>Objective: </strong>The purpose of the present study was to determine the clinical and cerebrospinal fluid profile of childhood encephalitis and to document Herpes simplex antibody status in cerebrospinal fluid.</p> <p><strong>Methodology: </strong>This descriptive analytical study was conducted in Department of Paediatrics of Shaheed Suhrawardy Medical College Hospital and Dhaka Medical College Hospital from May 2011 to October 2011. A total of 30 children of encephalitis were included in this study. Cerebrospinal fluid (CSF) routine and Herpes Simplex virus (HSV) antibody in CSF were done to all patient.</p> <p><strong>Result: </strong>Fever and convulsion was found in 29(96.7%) and 28(93.3%) cases respectively in studied patients. Altered level of consciousness was present in 29(96.7%) cases. Fever, convulsion and altered level of consciousness was statistically significant (p&lt;0.05). Glasgow coma scale (GCS) between 4 to 8 was found in 27 (90%) cases. Signs of meningeal irritation and cranial nerve palsies was found in 9 (30%) and 4 (13.3%) cases respectively. Exaggerated deep reflex was found in 23 (76.6%) cases whereas diminished deep reflex was found in 7 (23.3 %) cases. In cytological study of CSF, lymphocyte was found in 28 (93.3%) patients. Raised protein was found in 16(53.3%) and normal in 14 (46.7%) cases. Among the 30 studied cases 9(30%) cases were IgG positive for HSV, 21 (70.0%) were IgG negative and none were IgM positive.</p> <p><strong>Conclusion: </strong>Fever, convulsion, altered sensorium and low GCS were common clinical profile in children. Normal colour, increase lymphocyte count, normal sugar level were significant findings in CSF study.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):8-11</p> Sk. Serjina Anwar, Nazma Begum, Soofia Khatoon, Rafia Rashid ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Phenotypic and Genotypic Isolation of MRSA from Burn Wound Infected Patients at a Tertiary Care Hospital in Bangladesh <p><strong>Background: </strong>Patients of burn wound are generally more susceptible to infection due to concurrent status of malnutrition and immunosuppression. Among many bacteria, MRSA has appeared as a challenging pathogen irrespective of effective antibiotic therapy.</p> <p><strong>Objective: </strong>The purpose of the present study was to detect the prevalence and antibiogram of MRSA in burn wound infected patients.</p> <p><strong>Methodology: </strong>The present cross sectional study was conducted at Department of Microbiology in Rajshahi Medical College, Rajshahi, Bangladesh. The samples were collected from Burn and Plastic Surgery Unit of Rajshahi Medical College Hospital, for a period of one year. Phenotypic detection of MRSA were done by cefoxitin disc diffusion method and genotype (<em>mecA </em>gene) was detected by PCR which was conducted at Dhaka Medical College, Dhaka among all the <em>S. aureus </em>isolates.</p> <p><strong>Result: </strong>A total of 212 wound swabs were subjected to bacteriological culture media for isolation of MRSA and other organisms. As a whole 89.62% samples yielded growth in culture of which <em>Pseudomonas aeruginosa </em>was the predominant pathogen (34.18%). Out of 21 <em>S.aureus </em>isolates, 07(33.33%) were detected as MRSA by cefoxitin resistance and presence of <em>mecA </em>gene. Although over 85% MRSA were resistance to ciprofloxacin and ceftriaxone, but the present study could not detect any vancomycin resistant MRSA.</p> <p><strong>Conclusion: </strong>The high prevalence and decreased sensitivity of MRSA to commonly used antibiotics has been observed in Burn Unit of RMCH. Therefore it is necessary to establish an antimicrobial surveillance system in hospital settings to prevent the spread of MRSA.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):12-17</p> Anika Tasnim, AKM Shamsuzzaman, Md Shah Alam, Jannatul Ferdose, Fazlay Akbar Khan ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Status of Triple Antigen Test among Community Acquired Febrile Illness Patient attended at Tertiary Care Hospital, Bogura <p><strong>Background</strong>: Bacterial etiologies of febrile illnesses have significantly become important due to high mortality and morbidity.</p> <p><strong>Objective: </strong>This study aimed to identify the prevalence of rickettsial fever, brucellosis, and typhoid fever by triple antigen test.</p> <p><strong>Methodology: </strong>This cross-sectional study was conducted at TMSS Medical College Bogura district in Bangladesh for 6 months. Febrile patients aged from 1 to 65 years of both sexes were recruited from the outpatient department of this Medical College Bogura. Blood sample were taken from all patients for antibody test by microscopic plate agglutination test according to manufacturer instruction.</p> <p><strong>Results: </strong>A total of 140 patients were enrolled and 74/140 (52.86%) patients were positive by any of three antigens, among them female were 54/74 (72.97%), most common age group was 21 to 30 years which was 22/74(29.73%), TO titre was greater than TH titre, which was 24/36 (66.66%).</p> <p><strong>Conclusion: </strong>The study has underscored the importance of febrile antigen detection for bacterial diseases including zoonosis such as ricketial fever, brucellosis and typhoid fever in febrile patient and thus reducing diagnostic dilemma of febrile diseases. However, further diagnostic tests for diagnosis of febrile illnesses also needed. This will be helpful for febrile patients to receive the correct diagnoses and facilitation of accurate and prompt treatment.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):18-21</p> Taslima Yasmin, Md Abdullah Yusuf, Mohammed Golam Mowla, Mst Jeneya Afrin, Shamima Akhter, Mohammed Abdur Nur Sayam ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 A Data Driven Model for Prediction of COVID-19 Outbreak in Bangladesh <p>COVID-19 disease due to Corona virus of type SARS-CoV-2 has emerged from Wuhan, China in December 2019 and now it has expanded through infection all over the world. Now-a-days, this is a disaster pandemic for almost every nation in the earth. Such novel Corona virus impacts on every country in the world without regarding country's race, nationality and economic status. In this study, an attempt has been made to propose a data driven model to know the present and future Corona virus situation of Bangladesh. It also predicts the cumulative infected people, disease propagation, doubling time and new cases of COVID-19 patients. The result shows that more than two lakh fifty thousand people will be infected by Corona virus and its effect will start to decrease by the mid of July and decline to disappear by the end of August. This study will help policy makers to take plan for healthcare system and management of various aspects related to the control and prevention of Corona virus outspread in Bangladesh.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):22-26</p> Tapan Kumar Roy, Brijesh P Singh ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Suggestions and Recommendations of Face Mask Usage during COVID 19 Pandemic <p>Rate of spread of SARS-CoV-2 and number of relevant deaths continue to elevate as the time elapses since its first outbreak. With no readily available curative treatment neither any effective vaccine till now to prevent the infection, practicing personal protection measures remain the only effective way to stay protected from its attack. Those who are directly exposed to the care of any confirmed or suspected COVID-19 patient, including the health care workers and caregivers, have been advised by the World Health Organization (WHO) and Centre for Disease Control and Prevention (CDC) to wear proper face masks or respirators following the guidelines. Transmission of corona virus occurs through respiratory droplets, close personal contact as well as touching stuff or surfaces polluted by the viral particles. However, several studies have already proven the effectiveness of using various face masks, according to the circumstances, in preventing the dissemination of COVID-19.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):27-32</p> Nafisa Abedin, Kazi Nabila Bushrah, Muhit Reza Md Muktadir, Raisa Abedin Disha, Saumitra Chakravarty ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Mental Health of School-Going Children during Existing Lockdown Situation Due to COVID-19 Pandemic in Bangladesh <p>During this epidemic of COVID-19, children are in need of much concentration and profound love of the senior family members. Although the measures taken by the organizations are necessary to prevent the spread of the novel coronavirus, they may be causing widespread mental health issues, including depression and loneliness. Therefore, it is imperative that parents have to spend the lion-share of time with children while listening to them cordially. Parents can participate in sports with them to help them stay fit so that they can enjoy commemorating moments. However, in this additional time, the parents can also make them habituated to practice the rules of health, so does social distancing.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):33-37</p> Muhammad Anwar Hossain, Sanjida Rahman, Md Rezaul Karim ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 Global Outbreaks of SARS-nCoV-2 (COVID-19 Pandemic) and Spread out in Bangladesh <p>Currently, the world is concerned about the 2019 novel CoV (SARS-nCoV-2), the disease it causes has been named “coronavirus disease 2019” (COVID-19) that was initially identified in Wuhan, China on 31 December 2019. Infected patients presented with severe viral pneumonia and respiratory illness. The new SARS-CoV-2 is RNA genomes and a beta-coronavirus, like SARS-CoV and MERS-CoV. In this article, provide a brief insights into past and present outbreaks of COVID-19. At end of the April 2020, COVID-19 Pandemic spread out all over the world in 210 countries/areas and the number of confirmed cases has been mounting globally. Reported in USA alone, over one million people are infected which is one-third of world confirmed cases and deaths cases also near to one-fourth of the total estimated deaths cases so far recorded globally. In other countries of the world situation is almost same but in Europe COVID-19 positive cases so high including death cases. In Bangladesh, the number of confirmed cases and fatality rate is lower than other reported countries in the world, due to deficient testing facilities and inadequate number of samples are tested, the virus seems to be highly contagious in Bangladesh as well. Although the fatality rate of SARS-nCoV-2 is currently lower than SARS-CoV and MERS-CoV, but the virus seems to be highly contagious based on the number of infected cases to date.</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):38-41</p> Md Belal Hossain ##submission.copyrightStatement## Fri, 21 Aug 2020 00:00:00 +0000 When will we get the COVID-19 vaccine? <p>Abstract not available</p> <p>Bangladesh Journal of Infectious Diseases 2020;7(1):29-33</p> Siukan Law ##submission.copyrightStatement## Fri, 21 Aug 2020 10:54:26 +0000