TY - JOUR AU - Shavrov, Anton Andreevich AU - Kirgizov, Igor Vitalevich AU - Shavrov, Andrey Alexandrovich AU - Kharitonova, Anastasiya Yurevna AU - Talalaev, Alexander Gavrilovich AU - Volynets, Galina Vasilevna AU - Khomeriki, Sergei Germanovich PY - 2013/07/29 Y2 - 2024/03/29 TI - Confocal Laser Endomicroscopy in Diagnostics of Complications of Gastroesophageal Reflux Disease in Children JF - Bangladesh Journal of Endosurgery JA - Bangla J. Endosurg. VL - 1 IS - 2 SE - Original Articles DO - UR - https://www.banglajol.info/index.php/BJE/article/view/15930 SP - 1-6 AB - <p>Twenty-nine children with suspected gastroesophageal reflux disease (GERD) and 17 children as a reference group were enrolled in the study. A conventional white light endoscopy of the oesophagus was supplemented by a probe-based confocal laser endomicroscopy (pCLE) and followed by a biopsy for histological examination. A comparative analysis of endoscopic, endomicroscopic, and histological data were performed. The pCLE allows detecting oesophagitis with the sensitivity and specificity of 93% and 94%, respectively; gastric and intestinal metaplasia typical for Barrett oesophagus with 83% and 100%, respectively; and polyps of the cardioesophageal passage with the sensitivity of 89% in patients with long-term GERD. Thus, this method allows taking an optical biopsy of pathological changes of esophageal mucosa just during the standard endoscopic investigation.</p><p>DOI: <a href="http://dx.doi.org/10.11593/bje.2013.0102.0012">http://dx.doi.org/10.11593/bje.2013.0102.0012</a></p><p>Bangladesh Journal of Endosurgery Vol.1(2) May 2013: 1-6</p> ER -