Congenital Heart Disease in a Tertiary Care NICU; Pattern, Risk Factors and Outcome

Authors

  • Sanjoy Kumer Dey Professor and Chairman, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Md Arif Hossain Medical Officer, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Faria Yasmin Senior Resident, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Ismat Jahan Associate Professor, Department of Neonatology, Room no 214, First floor, Block C, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbagh, Dhaka, Bangladesh
  • Mohammad Kamrul Hassan Shabuj Associate Professor, Department of Neonatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/bjch.v46i3.72675

Keywords:

Birth defect, Congenital heart disease, Diabetes mellitus, Newborn

Abstract

Background: Identification of congenital heart disease (CHD) is increasing, may be due to advancement of diagnostic technology and availability of trained man power. Several studies have been conducted in Bangladesh to identify the prevalence and pattern of CHD but paucity of data regarding etiology and outcome.

Objective: The aim of this study is to identify the frequency and risk factors of so that preventive measures can be taken.

Methods: This retrospective case control study was conducted in the neonatal intensive care unit (NICU), BSMMU, Dhaka from January 2021 to June 2022. All admitted neonates in NICU with the diagnosis of CHD were considered as cases. Twice number of newborn having gestational age and birth weight matched neonates diagnosed other than CHD in NICU were considered as control. Data were extracted from the Medical records of patient files and computer electronic data records of “Newborn Birth Defect (NBBD) surveillance in Bangladesh.” The level of significance was set at 5% (P <0.05).

Result: Total 914 patient were admitted during the study period among them 119 patient were CHD (frequency rate 13%). Mean birth weight and gestational age of CHD group were 2376±783.85g & 35.80±3.26 weeks respectively. About 85.7% had acyanotic CHD, among them most prevalent were atrial septal defect (42%) then patent ductus arteriosus (11.8%). Cyanotic CHD were 17 (14.3%). Maternal DM significantly increase the risk of developing CHD, Odd’s ratio 1.971 (CI: 1.182 - 3.285). Death were more in CHD group (34.5%) than control group (20.4%), p values = 0.005.

Conclusion: Frequency (13%) of congenital heart disease was high. Maternal diabetes mellitus increases the risk of developing CHD of their baby. Death were more among babies with CHD.

BANGLADESH J CHILD HEALTH 2022; VOL 46 (3) : 122-129

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Published

2024-05-07

How to Cite

Dey, S. K. ., Hossain, M. A. ., Yasmin, F., Jahan, I., & Hassan Shabuj, M. K. (2024). Congenital Heart Disease in a Tertiary Care NICU; Pattern, Risk Factors and Outcome. Bangladesh Journal of Child Health, 46(3), 122–129. https://doi.org/10.3329/bjch.v46i3.72675

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Original Articles