The pattern of Atopy in Childhood Nephrotic Syndrome-A Tertiary Hospital Study

Authors

  • Sabiha Akther Assistant Professor, Paediatrics, Kushtia Medical College, Bangladesh
  • Arml Kabir Professor of Paediatrics, Ad-Din Women Medical College, Dhaka, Bangladesh
  • SM Khosruzzaman Resident Physician, Kushtia Medical College, Bangladesh

DOI:

https://doi.org/10.3329/bjch.v45i1.55466

Keywords:

Asthma, Allergic rhinitis, Allergic conjunctivitis, Nephrotic Syndrome

Abstract

Background: Idiopathic nephrotic syndrome is a common renal disease in children. Various atopic disorders are found in 30%-60% cases with childhood nephrotic syndrome.

Objective: To evaluate the association of atopic disorders with childhood idiopathic nephrotic syndrome.

Methods: This case-control study was conducted in the Department of Paediatrics, Sir Salimullah Medical College Hospital from January 2012 to December 2012. Fifty children of idiopathic nephrotic syndrome between 2 to 10 years of age were included and the diagnosis was based on history, clinical features and laboratory evidence. Age and sex-matched controls were taken from pediatrics outdoor who attended for problems other than nephrotic syndrome. Data regarding atopic disorders in both groups were collected and then analyzed.

Results: Mean ages in this study were 5.32±2.88 years and 5.34±2.87 years in case and control respectively. The male-female ratio was 1.7: 1 in both groups. A positive history of atopy was present in 46.0% of cases and 20.0% in controls. Atopic disorders were asthma (42.0% vs. 20.0%), allergic rhinitis (30% vs. 10%), atopic dermatitis (0.0% vs. 2.0%) and allergic conjunctivitis (0.0% vs. 2.0%) found in cases and controls respectively. Bronchial asthma was frequently (37.5%) found in frequent relapse nephrotic syndrome compared to infrequent relapse and the first attack of nephrotic syndrome.

Conclusion: Children with idiopathic nephrotic syndrome had a higher incidence of atopy. Asthma and allergic rhinitis was found as common atopic disorders associated with childhood idiopathic nephrotic syndrome.

BANGLADESH J CHILD HEALTH 2021; VOL 45 (1) : 6-9

Downloads

Download data is not yet available.
Abstract
25
PDF
22

Downloads

Published

2021-09-05

How to Cite

Akther, S. ., Kabir, A. ., & Khosruzzaman, S. (2021). The pattern of Atopy in Childhood Nephrotic Syndrome-A Tertiary Hospital Study. Bangladesh Journal of Child Health, 45(1), 6–9. https://doi.org/10.3329/bjch.v45i1.55466

Issue

Section

Original Articles