Cardiovascular Changes in Children with Acute Lower Respiratory Tract Infection

  • Shahreen Kabir Registrar, Pediatric Cardiology, National Heart Foundation and Research Institute, Darus-salam, Dhaka
  • Soofia Khatoon Academic coordinator and Head, Department of Pediatrics, CWCH, Ashulia, Dhaka
  • Lutful Ehsan Fatmi Head of Department of Pediatrics, Holy Family Medical College and Hospital, Dhaka
  • Nazneen Akhter Banu Head of Department of Pediatrics, Sir Salimullah Medical College and Mitford Hospital, Dhaka
  • Arif Ahmed Mohiuddin Specialist, Department of Cardiac Surgery, United Hospital Limited, Gulshan, Dhaka
  • Rubina Afroz Rana Jr. Consultant (Pediatrics), NCCRFHD, Sher-E-Bangla Nagar, Dhaka
Keywords: Cardiovascular, CK-MB, Pneumonia, Bronchiolitis

Abstract

Background: Acute Lower Respiratory Tract Infections (ALRI), particularly Pneumonia and Bronchiolitis, are important causes of death in childhood in Bangladesh. The cardiovascular and respiratory systems function as a single unit and alteration in cardiorespiratory interactions, can cause significant changes in cardiac function. The objective of this study was to find out any electrical and functional changes, myocardial injury, frequency of heart failure and the outcomes in these patients with ALRIs.

Methodology: It was a prospective observational study carried out at DMCH from January to June 2012 on 35 consecutive children admitted with ALRI, which were further diagnosed as pneumonia or bronchiolitis using operational definitions. Heart failure cases were identified and all the cases were then evaluated for any cardiovascular changes.

Results: Most of the patients were male. ECG changes occurred in the form of tachycardia. Abnormal echocardiographic findings were noted in the form of pulmonary hypertension, left ventricular systolic (LV) dysfunction and tricuspid regurgitation. 82.9% had raised CK-MB and was significantly higher in patients with tachycardia and having abnormal echocardiographic changes. Nine patients developed heart failure, 3 of them had pulmonary hypertension along with LV systolic dysfunction and one of pulmonary hypertension and LV systolic dysfunction each. CK-MB was raised significantly in all the patients with heart failure.

Conclusion: Raised CK-MB, tachycardia out of proportion on ECG and pulmonary hypertension with left ventricular systolic dysfunction were common findings in patients with ALRI.

Bangladesh J Child Health 2019; VOL 43 (1) :27-34

Downloads

Download data is not yet available.
Abstract
502
PDF
162
Published
2019-04-28
How to Cite
Kabir, S., Khatoon, S., Fatmi, L., Banu, N., Mohiuddin, A., & Rana, R. (2019). Cardiovascular Changes in Children with Acute Lower Respiratory Tract Infection. Bangladesh Journal of Child Health, 43(1), 27-34. https://doi.org/10.3329/bjch.v43i1.41213
Section
Original Articles