Nephrogenic Diabetes Insipidus - A Rare Report of Two Affected Sibling

Authors

  • Rumana Riaaz Resident, Phase-B, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Mahbub Mutanabbi Associate Professor, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Kohinoor Jahan Shamaly Resident, Phase-B, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka
  • CA Kawser Professor, Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University, Dhaka

DOI:

https://doi.org/10.3329/bjch.v41i3.36956

Keywords:

Nephrogenic Diabetes Insipidus, congenital, antidiuretic hormone

Abstract

Nephrogenic Diabetes Insipidus (NDI) is a type of Diabetes Insipidus (DI) where distal nephrons are unresponsive to antidiuretic hormone resulting in polyuria and polydipsia. NDI can be congenital or acquired. There are very few cases of congenital NDI, more in sibs. Here we report two sibs affected with congenital NDI. Both of them presented with polyuria, polydipsia and failure to thrive since early infancy. In both cases, water deprivation tests and urine osmolality were done before and after DDAVP that suggested NDI and the acquired causes has been excluded. Both of them were treated with oral Hydrochlorothiazide and improved.

Bangladesh J Child Health 2017; VOL 41 (3) :193-195

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Published

2018-06-10

How to Cite

Riaaz, R., Mutanabbi, M., Shamaly, K. J., & Kawser, C. (2018). Nephrogenic Diabetes Insipidus - A Rare Report of Two Affected Sibling. Bangladesh Journal of Child Health, 41(3), 193–195. https://doi.org/10.3329/bjch.v41i3.36956

Issue

Vol. 41 No. 3 (2017)

Section

Case Reports