Nephrogenic Diabetes Insipidus is a Rare Complication of Chronic Kidney Disease - A Case Report

  • Tahmina Jesmin Resident Phase B, Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Md Habibur Rahman Professor of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Goalm Muinuddin Professor and Chairman of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Afroza Begum Associate Professor of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • Ranjit Ranjan Roy Associate Professor of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
  • M Moazzam Hossain Professor of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka
Keywords: Nephrogenic Diabetes Insipidus

Abstract

Nephrogenic Diabetes Insipidus (NDI) may occur as a complication of chronic kidney disease (CKD). The incidence of NDI is very rare. So recognition of this potential complication is very important. In our country, this rare complication is not yet reported. So, to make awareness among the paediatricians, we report a case of NDI as a rare complication of CKD. A 4-year old boy was admitted in the Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University (BSMMU) with the complaints of failure to thrive, refusal to feed, nausea and vomiting since 18- months of his age. For the last six months, he had also complaints of polyuria and polydipsia. In addition to this, he developed muscle pain, constipation, bowing of leg and occasional unexplained fever. He was moderately pale with deep sighing respiration and his blood pressure was above 95th centile for age and sex. His creatinine level was high with low TCO2 and calcium level. His plasma osmolality was very high while urine osmolality was inappropriately low which did not increase after desmopressin (nasal spray) administration. Initial treatment with Indomethacin was ineffective while the combination of hydrochlorothiazide and Indomethacin was effective and well tolerated.

DOI: http://dx.doi.org/10.3329/bjch.v37i1.15350

BANGLADESH J CHILD HEALTH 2013; VOL 37 (1) : 41-44

Downloads

Download data is not yet available.
Abstract
778
PDF
972
Published
2013-06-18
How to Cite
Jesmin, T., Rahman, M., Muinuddin, G., Begum, A., Roy, R., & Hossain, M. (2013). Nephrogenic Diabetes Insipidus is a Rare Complication of Chronic Kidney Disease - A Case Report. Bangladesh Journal of Child Health, 37(1), 41-44. https://doi.org/10.3329/bjch.v37i1.15350
Section
Case Reports