Clinical Significance of Cardiac Murmur in Neonate

  • Mohammad Monir Hossain Department of Neonatology, Bangladesh Institute of Child Health and Dhaka Shishu (Children) Hospital
  • Mohammad Nurul Akhtar Hasan Medical Officer, Dhaka Shishu (Children) Hospital
  • Mahfuza Shirin Department of Neonatology, Bangladesh Institute of Child Health and Dhaka Shishu (Children) Hospital
  • Mohammad Abdullah Al Mamun Medical Officer, Dhaka Shishu (Children) Hospital
  • Md Delwar Hossain Paediatrics, Sadar Hospital, Mowlovibazar
Keywords: Murmur, neonate, heart defect

Abstract

Background: There is a popular believe that cardiac murmurs are common in neonate and most are innocent or physiological. However, a cardiac murmur may be the first sign of a serious structural cardiac disease in neonate.

Objective: This study was conducted to determine the clinical significance of cardiac murmur as a sole clinical sign in neonate.

Methodology: Fifty neonates having cardiac murmur were selected from in-patient department of Dhaka Shishu Hospital from March 06 to October 06. Murmurs were clinically classified as innocent or significant murmur. Echocardiography was done for confirmation of the diagnosis and then patients were reclassified as innocent murmur and structural heart defect. And structural heart defects are further subdivided into physiological variant or significant heart defect.

Results: Sixty eight percent cases with murmur were found to have structural heart defect and 32% had innocent murmur. Among the cases with structural heart defect 70.6% were found to have significant heart defect and 29.4% were physiological variant. Clinical suspicion able to differentiate innocent murmur or structural heart defect (p <0.05) as well as physiological variant versus significant heart defect (p <0.05).
Conclusion: Confident exclusion of heart disease in the newborn period on clinical examination is probably possible by pediatricians or neonatologists. However, for confirmation of diagnosis, early echocardiographic evaluation is necessary.

DOI: http://dx.doi.org/10.3329/bjch.v34i2.10218

BJCH2010; 34(2): 56-61

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Abstract
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PDF
1801
Published
2012-03-29
How to Cite
Hossain, M., Akhtar Hasan, M., Shirin, M., Al Mamun, M., & Hossain, M. (2012). Clinical Significance of Cardiac Murmur in Neonate. Bangladesh Journal of Child Health, 34(2), 56-61. https://doi.org/10.3329/bjch.v34i2.10218
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Original Articles