Recurrent episodes of jaundice in a young man with Dubin-Jhonson syndrome

Authors

  • Md Abdul Wadud Resident Physician, Shaheed Sheikh Abu Naser Specialized Hospital, Khulna, Bangladesh
  • Muhammed Arshad Ul Azim Assistant Professor, Department of Nephrology, Shaheed Sheikh Abu Naser Specialized Hospital, Khulna, Bangladesh
  • Ashfaque Ahmed Siddique Assistant Professor, Sheikh Russel National Gastroliver Institute and Hospital, Dhaka, Bangladesh
  • Md Anwarul Kabir Professor, Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/birdem.v11i3.55227

Keywords:

aspergillosis, itraconzole

Abstract

Dubin-Johnson syndrome is a rare inherited disorder associated with a defect in the ability of hepatocytes to secrete conjugated bilirubin into bile. Patients usually present with chronic or recurrent attacks of jaundice with conjugated hyperbilirubinemia. A dark pigment accumulates in the liver,which is responsible for itscharacteristic black color.It is a benign condition with a normal life expectancy and no specific treatment is required. We report a case of Dubin-Johnson syndrome in a 20-year-old man with recurrent episodes of jaundice, whose laboratory data revealed a mild conjugated hyperbilirubinemia, remaining liver function tests were normal and diagnosis was confirmed by the presence of dark brown pigment on microscopy of liver biopsy.

BIRDEM Med J 2021; 11(3): 235-238

Downloads

Download data is not yet available.
Abstract
27
PDF
25

Downloads

Published

2021-08-22

How to Cite

Wadud, M. A. ., Ul Azim, M. A. ., Siddique, A. A. ., & Kabir, M. A. . (2021). Recurrent episodes of jaundice in a young man with Dubin-Jhonson syndrome. BIRDEM Medical Journal, 11(3), 235–238. https://doi.org/10.3329/birdem.v11i3.55227

Issue

Section

Case Reports