Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease on Maintenance Haemodialysis

  • Muhammad Abdur Razzak Registrar, Dept of Nephrology,Kurmitola General hospital, Dhaka Cantonment, Dhaka
  • Debasish Kumar Saha Junior Consultant, Dept of Critical Care Medicine, BIRDEM, Dhaka
  • Muhammad Ehsan Jalil Assistant Professor, Dept of Nephrology, MH Samorita Medical College and Hospital, Dhaka
  • Mohammad Omar Faruque Miah Senior Clinical Pathologist, Mymensingh Medical College Hospital, Mymensingh
  • Abu Noim Md Abdul Hai Registrar, Dept of Nephrology, National Institute of Kidney Diseases and Urology, Dhaka
  • Abdul Latif Associate professor and Head, Dept of Nephrology, Jalalabad Ragib Rabeya Medical College Hospital, Sylhet
  • Md Rasul Amin Assistant professor, Dept. of Cardiology, BSMMU, Dhaka
  • Tofael Ahammod Medical officer, Shariatpur Sadar Hospital, Shariatpur
  • Kaniz Fatima Consultant, Popular Diagnostic Centre Limited, Dhaka
  • Shudhanshu Kumar Saha Registrar, Dept of Nephrology, BIRDEM, Dhaka
Keywords: Aortic stiffness; end stage renal disease; maintenance haemodialysis; risk estimation

Abstract

Background: The stiffness of the large elastic arteries increase the morbidity and mortality. The purpose of the present study was to estimate the risk of aortic stiffness among end stage renal disease patients on maintenance haemodialysis.

Methods: This cross-sectional study was carried out in the Department of Nephrology at National Institute of Kidney Diseases and Urology (NIKDU), Dhaka and National Institute of Cardiovascular Disease and Hospital (NICVD), Dhaka, Bangladesh from January 2013 to December 2014 for a period of two years. Chronic kidney disease in stage 5 [CKD-5(D)] patients older than 18 years on maintenance haemodialysis (MHD) for more than 3 months were designated as case group and age and sex matched non CKD patients were considered as control group. Serum calcium, serum albumin, serum phosphate and iPTH were estimated by semi-automated biochemistry analyzer from the Department of Biochemistry of NIKDU, Dhaka and NICVD, Dhaka. Plain Xray abdomen in lateral view was performed for all patients.

Result: A total number of 100 patients were enrolled for this study of which 50 patients were in end stage renal disease (ESRD) group and the rest 50 patients were in non-CKD group. Mean (±SD) aortic stiffness index was significantly higher (P<0.001) among ESRD population (3.27±1.70) compared to non CKD group of population (2.00±0.73). Mean (±SD) serum calcium (corrected) level was significantly high (P<0.001) in ESRD patients (9.79±0.87) compared to non CKD group of population (9.13±0.70). Mean (±SD) serum phosphate level was significantly higher (P<0.001) in ESRD patients (5.71±0.96) compared to non CKD group of population (4.20±0.59). However, mean (±SD) iPTH level showed no significant difference between ESRD (25.33±51.98) and non CKD group of population (38.53±19.52).

Conclusion: In conclusion, aortic stiffness is significantly higher among ESRD subjects.

Birdem Med J 2019; 9(1): 59-62

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Author Biographies

Muhammad Abdur Razzak, Registrar, Dept of Nephrology,Kurmitola General hospital, Dhaka Cantonment, Dhaka

Dept of Nephrology

Debasish Kumar Saha, Junior Consultant, Dept of Critical Care Medicine, BIRDEM, Dhaka

Dept of Critical Care Medicine

Muhammad Ehsan Jalil, Assistant Professor, Dept of Nephrology, MH Samorita Medical College and Hospital, Dhaka

Dept of Nephrology

Abu Noim Md Abdul Hai, Registrar, Dept of Nephrology, National Institute of Kidney Diseases and Urology, Dhaka

Dept of Nephrology

Abdul Latif, Associate professor and Head, Dept of Nephrology, Jalalabad Ragib Rabeya Medical College Hospital, Sylhet

Dept of Nephrology

Md Rasul Amin, Assistant professor, Dept. of Cardiology, BSMMU, Dhaka

Dept. of Cardiology

Shudhanshu Kumar Saha, Registrar, Dept of Nephrology, BIRDEM, Dhaka

Dept of Nephrology

Published
2019-01-12
How to Cite
Razzak, M. A., Saha, D., Jalil, M. E., Miah, M. O., Hai, A. N., Latif, A., Amin, M. R., Ahammod, T., Fatima, K., & Saha, S. (2019). Risk Estimation of Aortic Stiffness in Patients with End Stage Renal Disease on Maintenance Haemodialysis. BIRDEM Medical Journal, 9(1), 59-62. https://doi.org/10.3329/birdem.v9i1.39726
Section
Original Articles