Nutritional and therapeutic potential of Glycyrrhiza glabra L. roots

  • Fatma Hussain Clinico-Medical Biochemistry Laboratory, Department of Biochemistry, Faculty of Sciences, University of Agriculture, Faisalabad-38040, Pakistan
  • Irum Iqbal Clinico-Medical Biochemistry Laboratory, Department of Biochemistry, Faculty of Sciences, University of Agriculture, Faisalabad-38040, Pakistan
Keywords: cytotoxic; food additives; Glycyrrhiza glabra; root extracts; therapeutic

Abstract

This study was aimed to estimate the antioxidant, anti-diabetic, anti-amnesic, anti-biofilm, thrombolytic, hemolytic, and cytotoxic effects of G. glabra root extracts for nutritive and medicinal purpose. Antioxidant, alpha amylase, antiglycation, anti-amnesic, cytotoxic, thrombolytic and antibiofilm assays were performed. In the current research, G. glabra root extracts showed significant antioxidant (80.96 mg GAE/100 g TPC, 38.96 mg CE/100 g TFC, 46% DPPH scavenging), antidiabetic (75% antiglycation, 38.7% α-amylase inhibition), anti-amnesic (5.5%), hemolytic (19.46%), thrombolytic (35.4%) and antibiofilm (72% P. multocida, 51.57% S. aureus inhibition) activities. G. glabra root extracts have remarkable activity to fight against oxidative stress, hyperglycemia, blood coagulation, bacterial growth, DNA damage and memory enhancing ability that ensure its uses in food and pharmaceutical industries.

Asian J. Med. Biol. Res. June 2019, 5(4): 265-270

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Published
2020-02-03
How to Cite
Hussain, F., & Iqbal, I. (2020). Nutritional and therapeutic potential of Glycyrrhiza glabra L. roots. Asian Journal of Medical and Biological Research, 5(4), 265-270. https://doi.org/10.3329/ajmbr.v5i4.45263
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