Disturbance in glucose metabolism in patients with lichen planus

A. S. M. Zakaria, Md. Kamal Hossain, Mohammed Saiful Islam Bhuiyan, Abida Sultana, Mahmudur Rahman, Ommey Kulsom

Abstract

The aim of this study was to see the association of lichen planus (n=80) with glucose metabolism disturbance. Classic variety of lichen planus was the most common (76.3%), followed by ashy dermatosis, hypertrophic, oral, actinic and nail lichen planus. The blood glucose level 2 hours after glucose drink was abnormal in 20 cases. HbA1c was abnormal in 7 cases. The mean homeostasis model of assessment formulation- insulin resistance index (HOMA-IR) was 2.1 ± 1.6 and it was higher (>4.8) in 12.5% patients. Diabetes mellitus was found in 30 patients. Impaired glucose tolerance was found in 15 cases and high HOMA-IR was found in 10 cases. Total number of cases of abnormal glucose metabolism was found in 55 (68.8%) cases of lichen planus. In conclusion, patients with lichen planus  have higher risk of abnormal glucose metabolism specially diabetes mellitus.

Keywords

Glucose metabolism; Lichen planus

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DOI: http://dx.doi.org/10.3329/bsmmuj.v9i4.29993