Neurological findings and outcome in adult cerebral malaria

M.A. Sattar, Hasnat Waheedul Hoque, M. Robed Amin, M.A. Faiz, M. Ridwanur Rahman

Abstract

The neurological findings of 100 patients of adult cerebral malaria were studied. The commonest neurological feature was symmetrical upper motor neuron lesion as evidenced by exaggerated tendon reflexes and bilateral planter extensor (61%). Twenty two percent had features of meningeal irritation and/or meningism. Abnormal posturing occurred decerebrate rigidity (6%) and decorticate rigidity (4%) with or without opisthotonus, focal neurological deficit was noted in 5% cases. Pupillary size and reaction were normal in 86%, poor in 14%. Corneal reflexes were absent in 4% cases. Fundoscopy showed retinal hemorrhage in 16%, papilloedema is 3% and exudates in 1%. Majority of the patients recovered (80%) without any persistent neurological sequelae at the time of discharge from hospital and death rate was 20%.  Patients having focal neurological deficit, disconjugate gaze, poor pupillary reaction, absent corneal reflex and papilloedema were more susceptible to death. Delay in hospitalization and deep coma were also associated with increased mortality, whereas early hospitalization and proper nursing care could reduce mortality.

Keywords: Cerebral malaria; Neurological; Bangladesh

Online: 21 May 2009

DOI: 10.3329/bmrcb.v35i1.2313

Bangladesh Med Res Counc Bull 2009; 35: 15-17

Keywords

Cerebral malaria; Neurological; Bangladesh

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DOI: http://dx.doi.org/10.3329/bmrcb.v35i1.2313

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This peer-reviewed open access journal is indexed in PubMed/MEDLINE.