Protective effect of dried fruits of Carica papaya on hepatotoxicity in rat

Md. Zafor Sadeque, Zinnat Ara Begum

Abstract

Aqueous and ethanol extracts of Carica papaya has been evaluated for its hepatoprotective activity in rat. The aqueous and ethanol extracts of Carica papaya showed significant hepatoprotection against carbon tetrachloride induced hepatotoxicity. The protective activity was evaluated by using biochemical parameters such as serum bilirubin, serum alanine amino transferase (ALT), aspartate amino transferase (AST) and alkaline phosphatase. The histopathological changes of liver were compared with control.

Keywords: Carica papaya; hepatoprotective; rat

Online: 26 July 2010

DOI: 10.3329/bjp.v5i1.5305

Bangladesh J Pharmacol 2010; 5: 48-50

Keywords

Carica papaya; hepatoprotective effect; CCl4
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