Prompt Response to single injection of Bevacizumab in a case of Fibrinous Central Serous Choroidopathy (CSC).

Authors

  • Balbir Khan Department of Ophthalmology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab
  • Rajwinder Kaur Department of Ophthalmology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab
  • Vartika Anand Department of Ophthalmology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab
  • Prithpal S Matreja Department of Pharmacology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab

DOI:

https://doi.org/10.3329/bjms.v16i1.31152

Keywords:

Central serous choroidopathy, visual function, fibrin, bevacizumab

Abstract

Purpose: Central Serous Choroidopathy (CSC) is a disease of young and middle aged adults as a localized detachment of the neurosensory retina. Though the cause of CSC remains unknown, it is believed that abnormalities in choroidal circulation make overlying retinal pigment epithelium dysfunctional, resulting in development of a serous retinal detachment. Subretinal fibrin accumulation is rare but vision threatening association of CSC.

Methods: A young 31 years female with acute central serous chorioretinopathy received an Intravitreal bevacizumab (1.25 mg/0.05 ml) injection. At baseline and follow-up visits, patients had best corrected visual acuity (BCVA), IOP assessment, dilated fundus examination, fundus photography, fluorescein angiography (FA), and Optical Coherence Topography(OCT) imaging.

Results: Patient showed resolution of fibrin, resolution of intraretinal or subretinal fluid promptly, and improvement in visual symptoms and acuity within 1 month. At 6 months patient is maintaining 20/20 vision without any recurrence.

Conclusions: Intravitreal bevacizumab injection for acute fibrinous central serous choroidopathy may result in prompt resolution of neurosensory detachment and reduction of angiographic leakage. These short-term results suggest that Intravitreal bevacizumab injection may constitute a promising therapeutic option in fibrinous central serous chorioretinopathy.

Bangladesh Journal of Medical Science Vol.16(1) 2017 p.157-160

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Author Biography

Balbir Khan, Department of Ophthalmology, Gian Sagar Medical College and Hospital, Banur, Patiala, Punjab



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Published

2017-01-16

How to Cite

Khan, B., Kaur, R., Anand, V., & Matreja, P. S. (2017). Prompt Response to single injection of Bevacizumab in a case of Fibrinous Central Serous Choroidopathy (CSC). Bangladesh Journal of Medical Science, 16(1), 157–160. https://doi.org/10.3329/bjms.v16i1.31152

Issue

Section

Case Reports