A review of adult head and neck soft tissue sarcoma in a tertiary centre: malaysia experience

Authors

  • Salman Amiruddin Medical Lecturer, Universiti Sultan Zainal Abidin, Terengganu
  • Mohd Razif Muhamad Yunus Associate Professor, Consultant Otorhinolaryngology, Hospital Censelor Tuanku Muhriz,Universiti Kebangsaan Malaysia, Kuala Lumpur
  • Marina Mat Baki Associate Professor, Consultant Otorhinolaryngology, Hospital Censelor Tuanku Muhriz, Universiti Kebangsaan Malaysia, Kuala Lumpur

DOI:

https://doi.org/10.3329/bjms.v16i1.31136

Keywords:

Head and neck, soft tissue sarcoma, surgery, margin, radiotherapy, chemotherapy, prognosis

Abstract

Background: Head and neck tissue sarcoma are rare with potential high morbidity and mortality. The purpose of the present study was to present these cases and determine the optimal treatment for adult patients with head and neck soft tissue sarcomas.

Methods: It is a retrospective study of adult head and neck soft tissue sarcoma conducted in the Department of Otorhinolaryngology at Universiti Kebangsaan Malaysia Medical Centre (UKMMC) which is one of the national referral center within the period of 16 years from 1998 till 2014.

Results: Fourteen cases were reviewed in which7 histopathological variations of soft tissue sarcomas were identified. Local control after surgery alone or combined with radiotherapy was obtained in 50 % of the patients which is influenced by histologic grade, tumor size, and surgical margins. Patients with high-grade tumors or positive margins have improved local control if adjuvant radiotherapy is used. Distant metastases occurred in 14.2 % of patients and the 5-year survival rate was 50 %.

Conclusions: The optimal treatment for adult head and neck soft tissue sarcomas is surgery. Adjuvant radiotherapy improves outcomes for those with high-grade tumors or positive margins.

Bangladesh Journal of Medical Science Vol.16(1) 2017 p.69-76

Downloads

Download data is not yet available.
Abstract
1235
PDF
1170

Author Biography

Salman Amiruddin, Medical Lecturer, Universiti Sultan Zainal Abidin, Terengganu



Downloads

Published

2017-01-16

How to Cite

Amiruddin, S., Yunus, M. R. M., & Baki, M. M. (2017). A review of adult head and neck soft tissue sarcoma in a tertiary centre: malaysia experience. Bangladesh Journal of Medical Science, 16(1), 69–76. https://doi.org/10.3329/bjms.v16i1.31136

Issue

Vol. 16 No. 1 (2017)

Section

Original Articles

License

Authors who publish in the Bangladesh Journal of Medical Science agree to the following terms that:

  1. Authors retain copyright and grant Bangladesh Journal of Medical Science the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Bangladesh Journal of Medical Science are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0.This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  3. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.