Larvicidal activity of Cestrum nocturnum on Aedes aegypti

Chetan Jawale, Rambhau Kirdak, Laxmikant Dama



Aedes aegypti is a vector parasite of the Dengue. New method to control the population of this insect is necessary. In the present work we evaluated the potential of extract from Cestrum nocturnum as larvicide. Methanol extract outstand as highly active larvicide, achieving  100 % larval mortality in 24 hours when tested in the concentration of 45 µg/mL (soxhlet) and 25 µg/mL (percolation). Any extract exhibiting significant larvicide activity was further fractioned and the fraction tested according to the WHO protocol. One fraction derived from methanol extract present remarkable LC100 at 12 µg/mL. LC50 of methanol extract and active fraction were found 14 µg/mL and 6 µg/mL respectively. These fractions will be submitted to further fractions aiming to identify the molecules responsible for the larvicide activity.


Keywords: Aedes aegypti; Cestrum nocturnum; Dengue fever; Larvicidal

Online: 2 June 2010


DOI: 10.3329/bjp.v5i1.4714

Bangladesh J Pharmacol 2010; 5: 39-40







Aedes aegypti; Cestrum nocturnum; Dengue fever; Larvicidal

Full Text:



Bangladesh Journal of Pharmacology (Bangladesh J Pharmacol) is the peer-reviewed, open access official publication of the Bangladesh Pharmacological Society. Papers are published immediately after acceptance.

Study Pharmacology for Bangladeshi Medical Students


Abstracted/indexed in (19): Academic Search Complete, Agroforestry Abstracts, Arts & Humanities Citation Index, Asia Journals Online, Bangladesh Journals Online, Biological Abstracts, BIOSIS Previews, CAB Abstracts, Current Abstracts, Directory of Open Access Journals, EMBASE/Excerpta Medica, Forest Products Abstracts, Google Scholar, HINARI (WHO), International Pharmaceutical Abstracts, Open J-gate, Science Citation Index Expanded, SCOPUS and Social Sciences Citation Index.

For longterm preservation, the journal has been archived in the e-Depot archive.


Available in institutional webpage (20): Bangabandhu Sheikh Mujib Medical University; Eastern Michigan University Library;Halmstad University, Sweden; John Hopkins University; National Taiwan University; Oxford University; San Jose State University; Tel Aviv University; Tokyo University of Agriculture; University of Hong Kong; University of Maine; University of Nevada; University of North Carolina; University of Oklahama; University of Saskatchewan; University of Toronto; University of Washington; University of Windsor; Vrije Universiteit Brussel; York University

The Bangladesh Journal of Pharmacology does not accept responsibility for views expressed in articles, mini-reviews, and other contributions that appear in its pages.